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Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_plus |
| GeneSet | NCI_SIGNALING EVENTS MEDIATED BY STEM CELL FACTOR RECEPTOR (C-KIT) |
| Enrichment Score (ES) | -0.64101374 |
| Normalized Enrichment Score (NES) | -1.7177082 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.14606959 |
| FWER p-Value | 0.663 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | AKT1 | 1416657_at 1425711_a_at 1440950_at 1442759_at | 525 | 1.916 | 0.0393 | No | ||
| 2 | MATK | 1421739_a_at 1432329_a_at | 1998 | 0.748 | -0.0033 | No | ||
| 3 | HRAS | 1422407_s_at 1424132_at | 2039 | 0.734 | 0.0192 | No | ||
| 4 | STAT3 | 1424272_at 1426587_a_at 1459961_a_at 1460700_at | 2871 | 0.513 | -0.0019 | No | ||
| 5 | RPS6KB1 | 1428849_at 1446376_at 1454956_at 1457562_at 1459951_at 1460705_at | 6240 | 0.226 | -0.1482 | No | ||
| 6 | GRB10 | 1425457_a_at 1425458_a_at 1430164_a_at 1440935_at 1441620_at 1446921_at | 6623 | 0.211 | -0.1587 | No | ||
| 7 | BAD | 1416582_a_at 1416583_at | 8347 | 0.154 | -0.2323 | No | ||
| 8 | EPOR | 1423344_at | 8436 | 0.151 | -0.2314 | No | ||
| 9 | PTEN | 1422553_at 1441593_at 1444325_at 1450655_at 1454722_at 1455728_at 1457493_at | 9442 | 0.123 | -0.2732 | No | ||
| 10 | CBL | 1434829_at 1446608_at 1450457_at 1455886_at | 9569 | 0.120 | -0.2750 | No | ||
| 11 | SNAI2 | 1418673_at 1447643_x_at | 10213 | 0.103 | -0.3010 | No | ||
| 12 | DOK1 | 1417790_at | 11099 | 0.081 | -0.3387 | No | ||
| 13 | SPRED1 | 1423160_at 1423161_s_at 1423162_s_at 1428777_at 1441517_at 1442859_at 1443652_x_at 1445228_at 1452911_at 1460116_s_at | 11822 | 0.062 | -0.3697 | No | ||
| 14 | MAP2K2 | 1415974_at 1443436_at 1460636_at | 12229 | 0.053 | -0.3865 | No | ||
| 15 | PTPN11 | 1421196_at 1427699_a_at 1451225_at | 12683 | 0.041 | -0.4058 | No | ||
| 16 | MAPK8 | 1420931_at 1420932_at 1437045_at 1440856_at 1457936_at | 13273 | 0.025 | -0.4319 | No | ||
| 17 | JAK2 | 1421065_at 1421066_at | 13301 | 0.024 | -0.4323 | No | ||
| 18 | SPRED2 | 1423001_at 1434403_at 1436892_at 1441415_at 1441802_at | 13352 | 0.023 | -0.4338 | No | ||
| 19 | KITLG | 1415854_at 1415855_at 1426152_a_at 1440621_at 1448117_at | 13685 | 0.013 | -0.4485 | No | ||
| 20 | PTPRO | 1417676_a_at 1425863_a_at 1457771_at | 14775 | -0.024 | -0.4975 | No | ||
| 21 | PIK3R1 | 1425514_at 1425515_at 1438682_at 1444591_at 1451737_at | 15150 | -0.039 | -0.5133 | No | ||
| 22 | PIK3CA | 1423144_at 1429434_at 1429435_x_at 1440054_at 1453134_at 1460326_at | 16083 | -0.086 | -0.5530 | No | ||
| 23 | SHC1 | 1422853_at 1422854_at | 16122 | -0.088 | -0.5518 | No | ||
| 24 | KIT | 1415900_a_at 1452514_a_at 1459588_at | 16477 | -0.111 | -0.5643 | No | ||
| 25 | GAB1 | 1417693_a_at 1417694_at 1448814_at | 16627 | -0.123 | -0.5671 | No | ||
| 26 | MAP2K1 | 1416351_at | 16691 | -0.127 | -0.5658 | No | ||
| 27 | RAF1 | 1416078_s_at 1425419_a_at | 16963 | -0.150 | -0.5732 | No | ||
| 28 | GRB2 | 1418508_a_at 1449111_a_at | 17171 | -0.170 | -0.5770 | No | ||
| 29 | MITF | 1422025_at 1455214_at | 17279 | -0.183 | -0.5759 | No | ||
| 30 | SH2B3 | 1433455_at 1442756_at 1450183_a_at | 18040 | -0.283 | -0.6012 | No | ||
| 31 | MAPK3 | 1427060_at | 18642 | -0.385 | -0.6160 | No | ||
| 32 | SOS1 | 1421884_at 1421885_at 1421886_at | 18996 | -0.463 | -0.6168 | No | ||
| 33 | STAT5A | 1421469_a_at 1450259_a_at | 19066 | -0.479 | -0.6041 | No | ||
| 34 | GRAP2 | 1456432_at | 19875 | -0.712 | -0.6175 | Yes | ||
| 35 | PTPN6 | 1456694_x_at 1460188_at | 20072 | -0.789 | -0.6004 | Yes | ||
| 36 | VAV1 | 1422932_a_at | 20423 | -0.958 | -0.5848 | Yes | ||
| 37 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 20696 | -1.127 | -0.5600 | Yes | ||
| 38 | CRKL | 1421953_at 1421954_at 1425604_at 1436950_at | 20749 | -1.171 | -0.5237 | Yes | ||
| 39 | SOCS1 | 1440047_at 1450446_a_at | 21256 | -1.786 | -0.4878 | Yes | ||
| 40 | CREBBP | 1434633_at 1435224_at 1436983_at 1444856_at 1457641_at 1459804_at | 21262 | -1.794 | -0.4288 | Yes | ||
| 41 | PDPK1 | 1415729_at 1416501_at 1459775_at 1459776_x_at | 21761 | -3.077 | -0.3499 | Yes | ||
| 42 | STAT1 | 1420915_at 1440481_at 1450033_a_at 1450034_at | 21782 | -3.273 | -0.2428 | Yes | ||
| 43 | GSK3B | 1434439_at 1437001_at 1439931_at 1439949_at 1451020_at 1454958_at | 21811 | -3.432 | -0.1307 | Yes | ||
| 44 | TEC | 1441524_at 1460204_at | 21881 | -4.130 | 0.0025 | Yes |
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